Comparative automated assay of anti-P1 antibodies in acute hepatic distomiasis (fascioliasis) and in hydatidosis.

Abstract : An automated assay of anti-P1 allohemagglutinins has been carried out on 133 P2 subjects: 13 with acute hepatic distomiasis (Fascioliasis), 20 with hydatidosis and 100 healthy blood donors. Anti-P1 were detected in 100% of the distomatid sera, in 50% of the hydatid and in 29% of the healthy individuals. When compared to a reference serum test (anti-P1 standard), their concentration was found to be weak in healthy subjects, moderate in hydatidosis and exceptionally increased in acute distomiasis (up to 5-6 times the standard anti-P1 level). The 2-mercaptoethanol treatment showed that even the increased distomatid anti-P1 sera were of an IgM nature. The respective origin, synthesis and strength of these allohemagglutinins are discussed and the advantages of using distomatid IgM anti-P1 as human sera test are emphasized.
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Article dans une revue
Vox Sanguinis, Wiley, 1980, 38 (3), pp.165-8
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https://hal.univ-antilles.fr/hal-00715441
Contributeur : Bernard Carme <>
Soumis le : samedi 7 juillet 2012 - 04:28:50
Dernière modification le : jeudi 21 décembre 2017 - 13:28:03

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  • HAL Id : hal-00715441, version 1
  • PUBMED : 7385756

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R. Ben-Ismail, P. Rouger, Bernard Carme, M. Gentilini, C. Salmon. Comparative automated assay of anti-P1 antibodies in acute hepatic distomiasis (fascioliasis) and in hydatidosis.. Vox Sanguinis, Wiley, 1980, 38 (3), pp.165-8. 〈hal-00715441〉

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