This lecture main goal will be to present a synthesis of the researches we have conducted during the last 15 years about the pre-Columbian occupation of the West Indies between 300 BC and 400 AD. Those researches have been realized in Martinique, Dominica, Marie-Galante, Guadeloupe, Antigua and Barbuda. They have been enriched by the work of others archaeologists in Grenada, St. Vincent, Montserrat, Nevis, St Kitts and St. Martin. This huge set of data give us the opportunity to analysis the West Indian Amerindian civilizations in a maritime and archipelagic perspective, falling out by this way with the traditional approach focused on the insularity concept. The last part of this research have been an experimental archaeology program about Amerindian navigation techniques. Thus, between 2008 and 2010 we have navigated on a 60 feet long traditional dugout canoes from island to island, from Grenada to Antigua following the road of ours ancestors.