Sickle cell disease patients with COVID‐19 in Guadeloupe: Surprisingly favorable outcomes - Université des Antilles Access content directly
Journal Articles eJHaem Year : 2022

Sickle cell disease patients with COVID‐19 in Guadeloupe: Surprisingly favorable outcomes

Abstract

We investigate risk factors for hospitalization and difference between sickle cell syndromes in a cohort of COVID-19 sickle cell disease (SCD) adult patients managed in the Reference Center of Guadeloupe. We retrospectively collected data of symptomatic SCD adult patients infected with SARS-CoV-2 between March and December 2020. Thirty-eight SCD adult patients with symptomatic COVID-19 infection were included during the first wave, representing 9.6% of the active patient file at our center. The median age (IQR) was 39 years (24-47). Four patients were obese and two had moderate renal failure. The median duration of symptoms (IQR) was 10 days (5-15). Seventeen (44.7%) patients were hospitalized, including two in intensive care unit (ICU) for acute chest syndrome. An 85-year-old SC patient with prostate cancer died. No difference was detected between inpatient and outpatient groups in terms of age, gender, BMI, SCD clinical complications, and in history SCD treatment. There was no difference for severity, hospitalization, length of stay, ICU stay, or death between SS or Sβ°-thal patients and SC or Sβ+-thal patients. These overall favorable outcomes among symptomatic patients may be related to the low prevalence of comorbidity known to be linked to the more severe forms of COVID-19, but also to the prompt coordinated management of SCD patients in the Reference Center.
Fichier principal
Vignette du fichier
eJHaem - 2022 - Bernit - Sickle cell disease patients with COVID%u201019 in Guadeloupe Surprisingly favorable outcomes.pdf (186.37 Ko) Télécharger le fichier
Origin Publisher files allowed on an open archive

Dates and versions

hal-03819530 , version 1 (18-10-2022)

Identifiers

Cite

Emmanuelle Bernit, Marc Romana, Scylia Alexis‐fardini, Vanessa Tarer, Pierre‐marie Roger, et al.. Sickle cell disease patients with COVID‐19 in Guadeloupe: Surprisingly favorable outcomes. eJHaem, 2022, 3 (3), pp.636-643. ⟨10.1002/jha2.449⟩. ⟨hal-03819530⟩
51 View
90 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More